ICE (Integrated Clinical trial Environment) is an innovative solution also available in a completely online version for the creation, in few simple steps, of Electronic Data Capture platforms (eCRF; Electronic Case Report Form). ICE has been launched in 2016 by Advice Pharma Group Srl, a company specialized in clinical data management and telemedicine services based in the Polihub, the business incubator of the Politecnico di Milano. ICE is a Saas (Software as a service) and allows the creation through an intuitive and fast editor of validated data collection platforms, even without any IT skill. The application (www.ice-crf.com) was developed to give the possibility to create a «virtual environment» in which every single professional, from the investigator to the data manager or from the clinical project manager to the clinical monitor, through few simple steps is able to build an eCRF or to enter data in the platform, maximizing their experience as a user.

Not only, through the online platform the various users can access several unique tools; from the audit trail manager to the report & export editor, from the agenda to follow and compare the monitoring visits, the Risk Based Monitoring module and, finally, to an integrated communication system (Ics).

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